Speeding up drug discovery – Glyconet & 48Hour Discovery
48Hour Discovery and Glyconet were recently featured by Global News https://globalnews.ca/video/8705661/health-matters-speeding-up-drug-discovery-new-covid-19-variant-now-dominant-in-alberta/
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48Hour Discovery
Data Visualization
We have our own unique Analysis Suite to perform a number of tasks:
- Convert Illumina FASTQ file to user-friendly sequence table.
- Perform comprehensive statistical analysis to identify putative binders.
- Deliver visualization of sequencing data in easy-to-interpret reports.
History Plot
Track the history of abundance between multiple rounds
20 x 20 Grid
Breakdown of the positions of Amino acids with the file
Volcano Plot
Quickly identify changes in data sets composed of replicate data
Heat Map
Visualize raw reads in different replicates and experiments
Cluster Map
Visualize related sequences in a color coded and clustered way
Sequence table
Processed sequencing data arranged in a table format
48HD Cloud
Not only are we at the cutting edge in ligand discovery, we are also developing new state of the art software to make the discovery process easier and faster. Since this software drastically improved the experience for our own scientists we have decided to make it available to others. Here are some of the features that you can take advantage of:
Search Engine
Thanks to academic partners we have a large amount of experiment results that can be searched and viewed. Not only that but we are able to utilize the same search functions to help you organize and keep track of your data as well and all with the security of knowing that your data can’t be seen by anyone else. Unless you want to share it with them.
Preview Data
Our data processing system allows you to preview your data before you donwload the raw version. We provide breakdowns of motifs, top 100 reads, frequencies and much more. We also have various switches to turn on and off features within our previews, Don’t need to see the nucleotide information? You can turn it off. Want everything normalized to PPM? Flip the switch and everything will be normalized.
Plan Sequencing
Use our Sequencing sheets to help plan for your next sequencing run. Assign your primers, pick your library and add other extra data that you’ll need. The simple interface allows sequencing runs to be set up quicker and easier than ever.
Analyze Your Data
Use our Sequencing sheets to help plan for your next sequencing run. Assign your primers, pick your library and add other extra data that you’ll need. The simple interface allows sequencing runs to be set up quicker and easier than ever.
Preview Our Cloud
With a large amount of publicly available you are able to use some of the features of the cloud without signing up. Why not take a look around and experiment with our system. Certain features are only available to clients as such are not accessable during the free preview so if you see anything missing, don’t worry thats only because its a preview.
Single Round ScreeninG
Single-round screening is applied when protein targets have defined binding sites e.g. antibodies. The outcome of such screening are linear epitope mapping or immunoprofiling. We recommend clients use our in-house linear or cyclic libraries
Multi-Round Screening
Multi-round screening is used to probe protein-protein interactions, or when targets are more complex, e.g. with shallow binding sites, or targets that form complex. In this case, we recommend clients using our cyclic, bicyclic, or GE-FBD/customized libraries.
Cloud Database
We operate a proprietary cloud database service to store all results. This service enables access to results from anywhere in the world, with any device. In addition, search data that some academic partners have made public is available.
48HD is profiled as a top glycomics company in a new Glyconet report.
As with genomics 20 years ago, glycomics is at a critical stage, a tipping point. Glycomics is expected…
48Hour Discovery and Fusion Pharmaceuticals to Develop Radiopharmaceuticals for the Treatment of Cancer Tumours
The goal of the collaboration is to discover novel, peptide-based radiopharmaceuticals for the treatment of various solid tumours.…
We have our own unique Analysis Suite to perform a number of tasks:
- Convert Illumina FASTQ file to user-friendly sequence table.
- Perform comprehensive statistical analysis to identify putative binders.
- Deliver visualization of sequencing data in easy-to-interpret reports.
Not only are we at the cutting edge in ligand discovery, we are also developing new state of the art software to make the discovery process easier and faster. Since this software drastically improved the experience for our own scientists we have decided to make it available to others. Here are some of the features that you can take advantage of:
With a large amount of publicly available you are able to use some of the features of the cloud without signing up. Why not take a look around and experiment with our system. Certain features are only available to clients as such are not accessable during the free preview so if you see anything missing, don’t worry thats only because its a preview.
